Publications
Featured Publications
Delayed Integration of Somatostatin Interneurons Into Visual Circuits
A Wang, KA Ferguson, J Gupta, VH Fan, S Sun, D Barson, MJ Higley, JA Cardin
Flexible Perceptual Encoding by Discrete Gamma Events
Q Perrenoud, AH de O Fonseca, A Airhart, J Bonanno, R Mao, JA Cardin
Spatiotemporally Heterogeneous Coordination of Cholinergic and Neocortical Activity
S Lohani, AH Moberly, H Benisty, B Landa, M Jing, Y Li, MJ Higley, JA Cardin
All Publications
Spatiotemporally Dynamic Noradrenergic Regulation of Cortical Networks
C Barnes, FA Cini, P Xu, JA Cardin
FLUX: Geometry-Aware Longitudinal Flow Matching With Mixture of Experts
J Ortega Caro, Y Zhang, HM Batchelor, S He, JA Cardin, S Saxena
Visual Experience Drives Functional Reorganization of Cortical GABAergic Circuits
S Sun, Y Yue, Z Li, Q Perrenoud, JA Cardin
Learning-Dependent Cholinergic Plasticity Reconfigures Cortical Circuit Dynamics
AH Moberly, JA Cardin, MJ Higley
Lateral Septal Inhibition of Nucleus Basalis Through Direct and Indirect Pathways in Focal Limbic Seizures
J Liu, LA Sieu, I Shi, V Doan, S Liu, C Sun, A Brodovskaya, J Kapur, JA Cardin, H Blumenfeld
Selective Changes in Cortical Cholinergic Signaling During Learning
JO Caro, HM Batchelor, S Lohani, D van Dijk, JA Cardin
Higher-Order Thalamic Input to Cortex Selectively Conveys State Information
GT Neske, JA Cardin
Slow and Fast Cortical Cholinergic Arousal Is Reduced in a Mouse Model of Focal Seizures With Impaired Consciousness
LA Sieu, S Singla, J Liu, X Zheng, A Sharafeldin, G Chandrasekaran, M Valcarce-Aspegren, A Niknahad, I Fu, N Doilicho, A Gummadavelli, C McCafferty, RB Crouse, Q Perrenoud, MR Picciotto, JA Cardin, H Blumenfeld
Traumatic Brain Injury Disrupts State-Dependent Functional Cortical Connectivity in a Mouse Model
S Bottom-Tanzer, S Corella, J Meyer, M Sommer, L Bolaños, T Murphy, S Quiñones, S Heiney, M Shtrahman, M Whalen, R Oren, MJ Higley, JA Cardin, F Noubary, M Armbruster, C Dulla
The Cousa Objective: A Long-Working Distance Air Objective for Multiphoton Imaging In Vivo
CH Yu, Y Yu, LM Adsit, JT Chang, J Barchini, AH Moberly, H Benisty, J Kim, BK Young, K Heng, DM Farinella, A Leikvoll, R Pavan, R Vistein, BR Nanfito, DGC Hildebrand, S Otero-Coronel, A Vaziri, JL Goldberg, AJ Ricci, D Fitzpatrick, JA Cardin, MJ Higley, GB Smith, P Kara, KJ Nielsen, IT Smith, SL Smith
Rapid Fluctuations in Functional Connectivity of Cortical Networks Encode Spontaneous Behavior
H Benisty, AH Moberly, S Lohani, D Barson, RR Coifman, G Mishne, JA Cardin, MJ Higley
Learning Integral Operators via Neural Integral Equations
E Zappala, AH de Oliveira Fonseca, JO Caro, AH Moberly, MJ Higley, JA Cardin, D van Dijk
VIP Interneurons Regulate Cortical Size Tuning and Visual Perception
KA Ferguson, J Salameh, C Alba, H Selwyn, C Barnes, S Lohani, JA Cardin
Beyond Rhythm - A Framework for Understanding the Frequency Spectrum of Neural Activity
Q Perrenoud, JA Cardin
Developmental Loss of ErbB4 in PV Interneurons Disrupts State-Dependent Cortical Circuit Dynamics
R Batista-Brito, A Majumdar, A Nuno, C Ward, C Barnes, K Nikouei, M Vinck, JA Cardin
Putting the Brakes on Synchrony: VIP Interneurons Tune Visually Evoked Rhythmic Activity
Q Perrenoud, JA Cardin
Spatiotemporal Dynamics in Large-Scale Cortical Networks
MJ Higley, JA Cardin
The Logic of Developing Neocortical Circuits in Health and Disease
IL Hanganu-Opatz, SJB Butt, S Hippenmeyer, N De Marco, JA Cardin, B Voytek, AR Muotri
Simultaneous Cortex-Wide Fluorescence Ca2+ Imaging and Whole-Brain fMRI
EMR Lake, X Ge, X Shen, P Herman, F Hyder, JA Cardin, MJ Higley, D Scheinost, X Papademetris, M Crair, RT Constable
Mesoscopic Imaging: Shining a Wide Light on Large-Scale Neural Dynamics
JA Cardin, MC Crair, MJ Higley
Developmental Loss of MeCP2 From VIP Interneurons Impairs Cortical Function and Behavior
JM Mossner, R Batista-Brito, R Pant, JA Cardin
Up and Down States of Cortical Neurons in Focal Limbic Seizures
Z Yue, I Freedman, P Vincent, J Andrews, C Micek, M Aksen, R Martin, D Zuckerman, Q Perrenoud, G Neske, L Sieu, X Bo, JA Cardin, H Blumenfeld
Simultaneous Mesoscopic and Two-Photon Imaging of Neuronal Activity in Cortical Circuits
D Barson, A Hamodi, X Shen, G Lur, RT Constable, JA Cardin, M Crair, MJ Higley
Mechanisms Underlying Gain Modulation in the Cortex
KA Ferguson, JA Cardin
Activation of Distinct Channelrhodopsin Variants Engages Different Patterns of Network Activity
NY Jun, JA Cardin
Functional Flexibility in Cortical Circuits
JA Cardin
Altered Hippocampal Interneuron Activity Precedes Ictal Onset
ML Miri, M Vinck, R Pant, JA Cardin
Loss of TrkB Signaling in Parvalbumin-Expressing Basket Cells Results in Network Activity Disruption and Abnormal Behavior
D Xenos, M Kamceva, S Tomasi, JA Cardin, ML Schwartz, FM Vaccarino
Inhibitory Interneurons Regulate Temporal Precision and Correlations in Cortical Circuits
JA Cardin
Sensation During Active Behaviors
L Busse, JA Cardin, ME Chiappe, MM Halassa, MJ McGinley, T Yamashita, AB Saleem
Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits
R Batista-Brito, M Vinck, KA Ferguson, JT Chang, D Laubender, G Lur, JM Mossner, VG Hernandez, C Ramakrishnan, K Deisseroth, MJ Higley, JA Cardin
Snapshots of the Brain in Action: Local Circuit Interactions Through the Lens of Gamma Oscillations
JA Cardin
Projection-Specific Visual Feature Encoding by Layer 5 Cortical Subnetworks
G Lur, M Vinck, L Tang, JA Cardin, MJ Higley
Optogenetic Stimulation of Cholinergic Brainstem Neurons During Focal Limbic Seizures: Effects on Cortical Physiology
F Furman, Q Zhan, B Lerner, J Motelow, J Meng, C Ma, G Buchanan, IB Witten, K Deisseroth, JA Cardin, H Blumenfeld
Waking State: Rapid Variations Modulate Neural and Behavioral Responses
MJ McGinley, M Vinck, J Reimer, R Batista-Brito, E Zagha, CR Cadwell, AS Tolias, JA Cardin, DA McCormick
Arousal and Locomotion Make Distinct Contributions to Cortical Activity Patterns and Visual Encoding
M Vinck, R Batista-Brito, U Knoblich, JA Cardin
Optical Neural Interfaces
MR Warden, JA Cardin, K Deisseroth
Noninvasive Optical Inhibition With a Red-Shifted Microbial Rhodopsin
AS Chuong, ML Miri, V Busskamp, GA Matthews, LC Acker, AT Sorensen, A Young, NC Klapoetke, MA Henninger, SB Kodandaramaiah, M Ogawa, SB Ramanlal, RC Bandler, BD Allen, CR Forest, BY Chow, X Han, Y Lin, KM Tye, B Roska, JA Cardin, ES Boyden
Optogenetics (Encyclopedia of Computational Neuroscience)
JA Cardin
Dissecting Local Circuits In Vivo: Integrated Optogenetic and Electrophysiology Approaches for Exploring Inhibitory Regulation of Cortical Activity
JA Cardin
A Critical Role for NMDA Receptors in Parvalbumin Interneurons for Gamma Rhythm Induction and Cognitive Function
M Carlen, K Meletis, JH Siegle, JA Cardin, K Futai, D Vierling-Claassen, C Ruhlmann, SR Jones, K Deisseroth, M Sheng, CI Moore, LH Tsai
Computational Modeling of Distinct Neocortical Oscillations Driven by Cell-Type Selective Optogenetic Drive: Separable Resonant Circuits Controlled by Low-Threshold Spiking and Fast-Spiking Interneurons
D Vierling-Claassen, JA Cardin, CI Moore, SR Jones
Neocortical Interneurons: From Diversity, Strength
CI Moore, EM Carlen, U Knoblich, JA Cardin
Cellular Mechanisms of Temporal Sensitivity in Visual Cortex Neurons
JA Cardin, R Kumbhani, D Contreras, LA Palmer
Targeted Optogenetic Stimulation and Recording of Neurons In Vivo Using Cell Type-Specific Expression of Channelrhodopsin-2
JA Cardin, EM Carlen, K Meletis, U Knoblich, F Zhang, K Deisseroth, LH Tsai, CI Moore
Driving Fast-Spiking Cells Induces Gamma Rhythm and Controls Sensory Responses
JA Cardin, EM Carlen, K Meletis, U Knoblich, F Zhang, K Deisseroth, LH Tsai, CI Moore
Pinacidil Induces Vascular Dilation and Hyperemia In Vivo and Does Not Impact Biophysical Properties of Neurons and Astrocytes In Vitro
R Cao, BT Higashikubo, JA Cardin, U Knoblich, R Ramos, MT Nelson, CI Moore, JC Brumberg
Cellular Mechanisms Underlying Stimulus-Dependent Gain Modulation in Primary Visual Cortex Neurons
JA Cardin, LA Palmer, D Contreras
Stimulus Feature Selectivity in Excitatory and Inhibitory Neurons in Primary Visual Cortex
JA Cardin, LA Palmer, D Contreras
Stimulus-Dependent Gamma (30-50Hz) Oscillations in Simple and Complex Fast Rhythmic Bursting Cells in Primary Visual Cortex
JA Cardin, LA Palmer, D Contreras
Sensorimotor Nucleus NIf Is Necessary for Auditory Processing but Not Vocal Motor Output in the Avian Song System
JA Cardin, JN Raksin, MF Schmidt
Noradrenergic Inputs Mediate State Dependence of Auditory Responses in the Avian Song System
JA Cardin, MF Schmidt
Auditory Responses in Multiple Sensorimotor Song System Nuclei Are Co-Modulated by Behavioral State
JA Cardin, MF Schmidt
Song System Auditory Responses Are Stable and Highly Tuned During Sedation, Rapidly Modulated and Unselective During Wakefulness, and Suppressed by Arousal
JA Cardin, MF Schmidt
Memory Suppressor Genes: Enhancing the Relationship Between Synaptic Plasticity and Memory Storage
JA Cardin, T Abel
Lucifer Yellow Filling of Area X-Projecting Neurons in the High Vocal Center of Female Canaries
S Benton, JA Cardin, TJ DeVoogd
Research
Flexible function is a core feature of brain circuits, particularly in the cerebral cortex where neurons participate in both local and long-range circuits to integrate sensory information and promote behavior.
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